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Item Type:Conference or Workshop contribution (Paper)Item Status:Live ArchiveAbstractIt is common wisdom to understand digital computing as the basis of an unprecedented intermediality, in which once distinct media forms find themselves reconstituted as the content (in McLuhan’s terms) of increasingly integrated and homogeneous devices of communication. Following N. Katherine Hayles’ definition of digitization as ‘the act of making something discrete rather than continuous’, however, I argue in this paper that in order to be able to understand the long history of digitization, we must attempt to think the period generally regarded as representing the origin of digital computing from the 1694 completion of Leibniz’s Step Reckoner onward as being only the most recent, and perhaps most technically and ideologically effective, instantiation of a surprisingly long standing discourse network, which expressed itself as much in the universalization of writing as it does now through the discrete systems of modern computing.
There is a growing recognition that current preclinical models do not reflect the tumor microenvironment in cellular, biological, and biophysical content and this may have a profound effect on drug efficacy testing, especially in the era of molecular targeted agents. Here, we describe a method to directly embed low passage patient tumor “derived tissue into basement membrane extract, ensuring a low proportion of cell death to anoikis and growth complementation by coculture with patient derived cancer associated fibroblasts (CAF). A range of solid tumors proved amenable to growth and pharmacologic testing in this 3D assay.
Dame Vivienne Westwood, his former partner, stated, McLaren was a very charismatic, special and talented person. When we were young ( I fell in love with Malcolm, I thought he was beautiful and I still do. Magazine, renown as a global punk zine in the early 90 states, 60 had Warhol, the 70 had McLaren, and we all have the Sex Pistols.
You deploy on tour you become everyone best friend, said Thompson. There a lot of people are counting on their mail, especially parcels. Parcels sent to military members may be shipped for free until Jan. It’s brought to you by Fandango Musical Players, a Summerside community group. Karen Mair spoke with the show’s director Shirley Anne Cameron. (Photos courtesy of Island Live)By submitting a comment, you accept that CBC has the right to reproduce and publish that comment in whole or in part, in any manner CBC chooses.